ABSTRACT
This is a retrospective study conducted at the National Center for Gastrointestinal and Liver disease in Khartoum, Sudan on patients diagnosed with inflammatory bowel disease (IBD) during the period between January 1990 and May 2001. The study was conducted to determine the pattern of presentation and management outcome of inflammatory bowel disease (IBD) among Sudanese patients. All patients underwent a colonoscopy/ sigmoidoscopy with histopathological diagnosis, or a barium study. Seventy three patients were diagnosed as Ulcerative colitis (UC), and twelve patients as Crohn's disease (CD). The majority of our patients with UC improved with medical treatment. We concluded that IBD is not a rare disease in Sudan, UC being more common than CD. The disease tends to be more common in men in both UC and CD.
Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Colitis, Ulcerative/diagnosis , Crohn Disease/diagnosis , Female , Humans , Infant , Male , Middle Aged , Retrospective Studies , Sudan/epidemiologyABSTRACT
This study was conducted to assess the frequency of gastroesophageal reflux disease (GERD) and Barrett's esophagus among Sudanese patients with clinical symptoms of heartburn. One hundred and five patients were included in the study; forty seven patients had evidence of reflux oesophagitis, 61.7% of whom had grade B oesophagitis according to the modified Los Angeles classification and 10.6% had Barrett's oesophagus. 78.7% of the biopsies from the esophageal cardia revealed presenced of inflammation (Carditis). Dysplasia was documented in 21.3% of these biopsies. Helicobacter pylori was detected 59.6% of gastrooesophageal reflux disease patients and 56.8% of patients with carditis. However, 80% of patients with Barrett oesophagus were positive for Helicobacter pylori. It was concluded that gastro-oesophageal reflux disease affects all age groups with males being affected more than females and Helicobacter pylori infection did not play a major role in gastro-oesophageal reflux disease orits complications.
Subject(s)
Adult , Esophagitis, Peptic/diagnosis , Esophagoscopy , Female , Gastroesophageal Reflux/diagnosis , Humans , Male , Middle Aged , Sudan/epidemiologyABSTRACT
An 8-month old Sudanese male child with a history of recurrent vomiting since the age of 4 months was referred for upper gastrointestinal edoscopy, which showed a dilated oesophagus and a tight lower esophageal sphincter. The child was diagnosed as having achalasia, which was successfully treated with pneumatic dilatation under General anaesthesia.